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VARI chief scientist joins elite ranks of
American Academy of Arts and Sciences

Meet the Jones Lab team!

Dr. Peter Jones elected to National Academy of Sciences to advise nation on medical and epigenomic policy and direction

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Phase II colorectal cancer
clinical trial first to receive
support, scientific oversight from
VARI-SU2C
Epigenetics Dream Team
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VARI is home to three Fellows of the AACR Academy.
Dr. Stephen Baylin, Dr. Peter Jones and Dr. George Vande Woude

Epigenetic Therapies

Jones Laboratory
Our laboratory is focused on the mechanisms by which epigenetic processes become misregulated in cancer and contribute to the disease phenotype. We focus on the role of DNA methylation in controlling the expression of genes during normal development and in cancer.

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NEWS

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In the Press

5 April 2017 Van Andel Institute installs world class microscope to help fight cancer
FOX 17 

29 March 2017 VARI invests $10M in microscope facility
Grand Rapids Business Journal

24 Sept. 2015 Catalyzing Progress in Epigenetics Research 
Cancer Research Catalyst – AACR

13 August 2015 Interview with Dr. Peter Jones on DNA methylation
The Naked Scientists

20 Oct. 2014 Van Andel Institute commits $7.5 million to Stand Up To Cancer “Dream Team” researching epigenetics
MLive

7 Oct. 2014 Fred Upton brings 21st Century Cures talks on fostering medical innovation to Kalamazoo
MLive

5 Sept. 2014 Grand Rapids scientist joins stars in Stand Up To Cancer telecast tonight
MLive

9 July 2014 Vision for Van Andel Institute: Lead scientist details plan for internationally known research center
MLive

25 Feb. 2014 VAI appoints world renowned doctor as director of research
WZZM

24 Feb. 2014 Van Andel Institute announces “historic moment” with plan for global epigenetics research hub
MLive

17 Dec. 2013 Van Andel Institute names CSO
Grand Rapids Business Journal

Recent Publications

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Roulois et al. DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts. Cell

Lay FD et al. The role of DNA methylation in directing the functional organization of the cancer epigenome. Genome Res

Yang X et al. Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell

Taberlay PC et al. Reconfiguration of nucleosome depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer. Genome Res

Su et al. A panel of three markers hyper- and hypomethylated in urine sediments accurately predicts bladder cancer recurrence. Clin Cancer Res

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